Free HESI A2 Anatomy & Physiology Practice Test

Test your knowledge with our free HESI A2 Anatomy and Physiology practice test. These challenging questions cover essential topics such as body systems, anatomical terminology, and physiological processes—key areas on the HESI exam. Each question includes a detailed explanation to support your learning.

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1. Question

Which of the following is NOT a function of the digestive tract?

2. Question

What is the best definition of homeostasis?

3. Question

Which best describes how the endocrine system works?

4. Question

Which anatomical directional term refers to a body part being located toward the front of the body?

5. Question

Where is Vitamin K created in the body?

6. Question

What is the largest organ in the body?

7. Question

A medical scientist studies the parenchyma of the kidney. What specific type of science is this?

8. Question

What is erythropoiesis?

9. Question

Which body part lacks keratin?

10. Question

What is the relationship between sarcomeres, myofibrils, and muscle cells?

11. Question

A person who has torn their vastus lateralis muscle will need which of the following?

12. Question

What is the shaft of a long bone called?

13. Question

What is primarily regulated by the medulla oblongata?

14. Question

Which of the following is true about simple reflexes?

15. Question

Estrogen serves what primary function in the female reproductive system?

16. Question

What is the name of the structure that transfers urine from the kidneys to the bladder?

17. Question

Humans can survive most easily without which of the following?

18. Question

Which of the following is NOT a role of cortisol?

19. Question

How many pairs of spinal nerves exit the spinal cord?

20. Question

Which organelles are hair-like extensions that move substances over a cell’s surface?

21. Question

What is the function of cyclic adenosine monophosphate (cAMP)?

22. Question

The neuron is composed of ____________, which transmit signals toward the cell body, and a(n) ____________, which transmits signals away from the cell body.

23. Question

Where is the pectoralis major muscle located?

24. Question

Which is a steroid hormone?

25. Question

Which pair of hormones regulates blood calcium homeostasis?

Next Practice Test: Biology

The neuron is composed of , which transmit signals toward the cell body, and a(n) , which transmits signals away from the cell body.